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Tréfa javaslat Is npc1 ssd részeg Mártír korábbi

Structural basis for itraconazole-mediated NPC1 inhibition | Nature  Communications
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications

Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1  and NPC2 - ScienceDirect
Structural Basis of Low-pH-Dependent Lysosomal Cholesterol Egress by NPC1 and NPC2 - ScienceDirect

NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis  and Is a Targetable Pathway in Niemann-Pick Type C - ScienceDirect
NPC1-mTORC1 Signaling Couples Cholesterol Sensing to Organelle Homeostasis and Is a Targetable Pathway in Niemann-Pick Type C - ScienceDirect

Guilty until proven innocent: the case of NPC1 and cholesterol: Trends in  Biochemical Sciences
Guilty until proven innocent: the case of NPC1 and cholesterol: Trends in Biochemical Sciences

Cholesterol transport in the lysosome. Upon being delivered to the... |  Download Scientific Diagram
Cholesterol transport in the lysosome. Upon being delivered to the... | Download Scientific Diagram

NPC1 and PTCH1* SSD structural and surface comparison a, NPC1 SSD. The... |  Download Scientific Diagram
NPC1 and PTCH1* SSD structural and surface comparison a, NPC1 SSD. The... | Download Scientific Diagram

Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1  and NPC2 Proteins | SpringerLink
Insights into the Molecular Mechanisms of Cholesterol Binding to the NPC1 and NPC2 Proteins | SpringerLink

Structure of human Niemann–Pick C1 protein | PNAS
Structure of human Niemann–Pick C1 protein | PNAS

3.3 Å structure of Niemann–Pick C1 protein reveals insights into the  function of the C-terminal luminal domain in cholesterol transport | PNAS
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS

3.3 Å structure of Niemann–Pick C1 protein reveals insights into the  function of the C-terminal luminal domain in cholesterol transport | PNAS
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS

Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick  C1 | eLife
Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1 | eLife

3.3 Å structure of Niemann–Pick C1 protein reveals insights into the  function of the C-terminal luminal domain in cholesterol transport | PNAS
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport | PNAS

Correction of Niemann-Pick type C1 disease with the histone deacetylase  inhibitor valproic acid | bioRxiv
Correction of Niemann-Pick type C1 disease with the histone deacetylase inhibitor valproic acid | bioRxiv

Signatures of natural selection and ethnic-specific prevalence of NPC1  pathogenic mutations contributing to obesity and Niemann–Pick disease type  C1 | Scientific Reports
Signatures of natural selection and ethnic-specific prevalence of NPC1 pathogenic mutations contributing to obesity and Niemann–Pick disease type C1 | Scientific Reports

A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport...  | Download Scientific Diagram
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport... | Download Scientific Diagram

The NPC1 protein: structure implies function - ScienceDirect
The NPC1 protein: structure implies function - ScienceDirect

Role of the SSD within NPC1 in mediating the binding between NPC1... |  Download Scientific Diagram
Role of the SSD within NPC1 in mediating the binding between NPC1... | Download Scientific Diagram

MARCH6 may contain a sterol sensing domain (A) % similarity of SSDs... |  Download Scientific Diagram
MARCH6 may contain a sterol sensing domain (A) % similarity of SSDs... | Download Scientific Diagram

Structural basis for itraconazole-mediated NPC1 inhibition | Nature  Communications
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications

NPC1 structure and proposed pathway of cholesterol binding (A)... |  Download Scientific Diagram
NPC1 structure and proposed pathway of cholesterol binding (A)... | Download Scientific Diagram

Figures and data in Inter-domain dynamics drive cholesterol transport by  NPC1 and NPC1L1 proteins | eLife
Figures and data in Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins | eLife

Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol  Transfer and Ebola Infection
Structural Insights into the Niemann-Pick C1 (NPC1)-Mediated Cholesterol Transfer and Ebola Infection

Structural basis for itraconazole-mediated NPC1 inhibition | Nature  Communications
Structural basis for itraconazole-mediated NPC1 inhibition | Nature Communications

A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport...  | Download Scientific Diagram
A working model of NPC1/NPC2-mediated LDL-derived cholesterol transport... | Download Scientific Diagram

NPC1, intracellular cholesterol trafficking and atherosclerosis. | Semantic  Scholar
NPC1, intracellular cholesterol trafficking and atherosclerosis. | Semantic Scholar